Critical Evaluation of P2X7 Receptor Antagonists in Selected Seizure Models
نویسندگان
چکیده
منابع مشابه
Critical Evaluation of P2X7 Receptor Antagonists in Selected Seizure Models
The ATP-gated P2X7 receptor (P2X7R) is a non-selective cation channel which senses high extracellular ATP concentrations and has been suggested as a target for the treatment of neuroinflammation and neurodegenerative diseases. The use of P2X7R antagonists may therefore be a viable approach for treating CNS pathologies, including epileptic disorders. Recent studies showed anticonvulsant potentia...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2016
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0156468